The information, statistical data and estimates contained herein have been obtained from sources believed to be reliable but do not purport to serve as a guarantee to accuracy and completeness and therefore should not be construed as same. Moreover, no undertaking or obligation is herein made to advise you or any reader or any potential investor as to any changes in estimated data or figures neither on an updated basis nor as to any changes in Viscogliosi Brothers, LLC, its affiliates, or subsidiaries opinions or recommendations. Viscogliosi Brothers, LLC, our affiliates, and subsidiaries and any member, manager, employee or agent or any member of their families (“VB”) may from time to time purchase or sell any of the herein mentioned or related publicly-traded or privately negotiated securities or serve as directors, officers or investment bankers of such business entity issuing said securities. All information herein is subject to change without notice and any recommendation or opinion contained herein may be unsuitable for certain investors based on their age, available assets, liabilities, tolerance for risk and other individual factors. Additional information, if available and no guarantee are made of same, will be provided upon request.

Viscogliosi Brothers, LLC and its affiliates and subsidiaries in the past, currently or anticipates in the future to maintain venture capital, private equity, debt, convertible debt and/or public securities investments in several companies mentioned in this report. Should you desire more information, please contact VB directly.

Through funds VB manages or through direct investment, VB may maintain long and short positions in the publicly-traded securities and derivative securities of musculoskeletal, orthopaedic and spine companies, as well as health care and other companies. These investment positions may change from time to time and VB does not represent, guarantee or undertake to inform you of any changes in VB’s investment positions or opinions concerning such investments.

Through various direct investments, venture capital and private equity funds, VB maintains venture capital and private equity and debt positions in the securities of several musculoskeletal, orthopaedic, spine and spine non-fusion companies. These investment positions may change from time to time and VB does not represent, guarantee or undertake to inform you of any changes in VB’s investment positions or opinions concerning VB’s investments.

Through an affiliate VB provides regulatory and clinical consulting and strategic advisory services to the global musculoskeletal industry. VB currently provides or anticipates providing regulatory and clinical consulting and strategic advisory services to several privately-held companies listed in this report, some of which VB maintains or may maintain an equity or debt interest.

© 2005 Viscogliosi Brothers, LLC, All Rights Reserved.